CDC Identifies Drug-Resistant Mpox Strain In US

Reuters reports:

U.S. health officials have identified a cluster of cases caused by an mpox variant that are resistant to Siga Technologies’antiviral tecovirimat, branded as TPOXX, in five U.S. states, federal and state researchers reported on Thursday.

The cases involved a total of 18 individuals infected with clade II mpox between Oct. 6, 2023, and Feb. 15, 2024, who had never taken the treatment before, according to the report published in the Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report.

Health officials said the latest cases are likely to have been underestimated because not all cases of mpox undergo genetic sequencing to determine the variant causing the infection.

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